Non-Cell Autonomous Roles for CASK in Optic Nerve Hypoplasia
نویسندگان
چکیده
منابع مشابه
Optic Nerve Hypoplasia
Congenital anomalies of the optic disc underlie many cases of decreased vision, strabismus, and nystagmus in childhood. A comprehensive evaluation necessitates an understanding of the ophthalmoscopic features, associated neuro-ophthalmologic findings, pathogenesis, and appropriate ancillary studies for each anomaly. The subclassification of different forms of “colobomatous” defects on the basis...
متن کاملSpectrum of optic nerve hypoplasia.
Optic nerve hypoplasia is a non-progressive condition characterised by subnormal vision and a subnormal number of optic nerve axons. It may be unilateral or bilateral, isolated or combined with other defects. Analysis of fundus photographs from a series of 7 patients with a stationary abnormality of different degrees showed that the functional defects could be closely correlated with defects in...
متن کاملHypoplasia of the optic nerve.
Hypoplasia of the optic nerve is uncommon (Scheie and Adler, I94I; Somerville, I962; Whinery and Blodi, I963; Ewald, I967). It is usually due to a failure of development of the ganglion cell layer of the retina and results in a small but discernible optic disc with central vessels. The disc may be cupped with a peripapillary, mottled, yellowish halo corresponding to the size of the normal disc,...
متن کاملIncidental bilateral optic nerve hypoplasia.
Harvey JP. BMJ Case Rep 2017. doi:10.1136/bcr-2017-220343 Description A 19-year-old man was incidentally noted to have a bitemporal heteronymous hemianopia on automated perimetry during his first optician’s sight test (figure 1). The patient reported life-long reduced vision in the right eye although this was his first presentation to ophthalmic services. The patient was induced at 34 weeks due...
متن کاملVisual field defects in optic nerve hypoplasia.
Case 1—A nine-year-old white girl was seen at the Bascom Palmer Eye Institute in December, 1969, because of poor vision. The parents first sus pected that she had decreased vision at age two and one-half years after a bout of measles. At the age of six years, two examiners had recorded her visual acuity at 20/200 in each eye. At the age of seven years, because of the poor vision and pale disks...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2019
ISSN: 1552-5783
DOI: 10.1167/iovs.19-27197